// Evidence Grader
Claim grades, A through F
Every major genomics claim in this course gets a transparent grade — from clinically established interventions to outright misleading marketing. Use this dashboard to audit what's settled, what's preliminary, and what's hype.
A
Clinically established
B
Supported, context-specific
C
Promising, preliminary
D
Plausible, unproven
E
Popular, weak support
F
Misleading or false
Filtered:← Back to module
F
ENCODE's '80% functional' claim means most of the genome is biologically essential
ENCODE used a maximally permissive 'biochemical activity' definition. Comparative-genomics estimates put functionally constrained sequence at ~8–15%.
Module 01 · The Human Genome at Scale →