// Evidence Grader

Claim grades, A through F

Every major genomics claim in this course gets a transparent grade — from clinically established interventions to outright misleading marketing. Use this dashboard to audit what's settled, what's preliminary, and what's hype.

A
Clinically established
B
Supported, context-specific
C
Promising, preliminary
D
Plausible, unproven
E
Popular, weak support
F
Misleading or false
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B
ACMG-recommended opportunistic secondary-finding return improves outcomes for some carriers
Plausible mechanism, supported by single-gene case series; controlled outcome data limited.
Module 12 · Ethics, Equity, and the Germline Question