// Evidence Grader

Claim grades, A through F

Every major genomics claim in this course gets a transparent grade — from clinically established interventions to outright misleading marketing. Use this dashboard to audit what's settled, what's preliminary, and what's hype.

A
Clinically established
B
Supported, context-specific
C
Promising, preliminary
D
Plausible, unproven
E
Popular, weak support
F
Misleading or false
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A
Smoking produces large, reproducible methylation changes at AHRR and F2RL3
EWAS-replicated dozens of times; among the strongest environmental epigenetic signals known.
Module 08 · Lifestyle Inputs to the Epigenome
A
Regular aerobic + resistance exercise produces methylation changes at exercise-responsive loci in skeletal muscle
Reproducible across multiple training studies (e.g. Lindholm 2014, Robinson 2017).
Module 08 · Lifestyle Inputs to the Epigenome