// Evidence Grader

Claim grades, A through F

Every major genomics claim in this course gets a transparent grade — from clinically established interventions to outright misleading marketing. Use this dashboard to audit what's settled, what's preliminary, and what's hype.

A
Clinically established
B
Supported, context-specific
C
Promising, preliminary
D
Plausible, unproven
E
Popular, weak support
F
Misleading or false
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A
GrimAge predicts all-cause mortality better than chronological age and earlier clocks
Lu et al. Aging 2019; replicated across multiple cohorts.
Module 07 · The Epigenome and Methylation Clocks →
A
EpiSign-style methylation profiling is a clinically actionable diagnostic for syndromic intellectual disability
>100 syndromes with validated episignatures; widely reimbursed in CA, EU.
Module 07 · The Epigenome and Methylation Clocks →